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Antimalarial Activities of Polyhydroxyphenyl and Hydroxamic Acid Derivatives

Several known mammalian ribonucleotide reductase inhibitors featuring a polyhydroxyphenyl and/or hydroxamate moiety as the active group were screened for potency in inhibiting growth of the malaria parasite Plasmodium falciparum. Compounds containing a 2,3- or 3,4-dihydroxyphenyl group as well as be...

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Detalhes bibliográficos
Main Authors: Holland, Kevin P., Elford, Howard L., Bracchi, Valerie, Annis, Charles G., Schuster, Sheldon M., Chakrabarti, Debopam
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC105855/
https://ncbi.nlm.nih.gov/pubmed/9736585
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