Influence of Human Serum on Pharmacodynamic Properties of an Investigational Glycopeptide, LY333328, and Comparator Agents against Staphylococcus aureus

The MICs and MBCs of 15 antibiotics for two strains of Staphylococcus aureus were determined in Mueller-Hinton broth (MHB) and 90% serum–10% MHB. Subsequent experiments established that highly protein-bound antibiotics (≥80%), such as LY333328, demonstrated higher MICs and MBCs, less killing over an...

ver descrição completa

Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Zhanel, George G., Kirkpatrick, Iain D. C., Hoban, Daryl J., Kabani, Amin M., Karlowsky, James A.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1998
Assuntos:	Susceptibility
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC105846/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9736576/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.42.9.2427
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!