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Pharmacokinetics of Pentoxifylline and Its Metabolites in Healthy Mice and in Mice Infected with Candida albicans

Pentoxifylline has immunomodulatory properties and has been shown to decrease organ damage and improve survival in animals with gram-negative sepsis or endotoxemia. This effect is mediated by a reduction in endotoxin-induced production of tumor necrosis factor alpha (TNF-α) by the host. In earlier s...

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Bibliografiske detaljer
Main Authors: Miller, Kenneth, Louie, Arnold, Baltch, Aldona L., Smith, Raymond P., Davis, Patrick J., Gordon, Morris A.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 1998
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC105841/
https://ncbi.nlm.nih.gov/pubmed/9736571
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