Efficacy of Nikkomycin Z in the Treatment of Murine Histoplasmosis

Immune-competent ICR and BALB/c athymic (nude) mice were infected intravenously with Histoplasma capsulatum and treated with either fluconazole or nikkomycin Z or 5% dextrose (controls). In immune-competent ICR mice, fluconazole and nikkomycin Z both prolonged survival when given at 5 mg/kg of body...

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Main Authors: Graybill, John R., Najvar, Laura K., Bocanegra, Rosie, Hector, Richard F., Luther, Michael F.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 1998
Fag:
Experimental Therapeutics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC105835/
https://ncbi.nlm.nih.gov/pubmed/9736565
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