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Association of a Thr-371 Substitution in a Conserved Amino Acid Motif of Penicillin-Binding Protein 1A with Penicillin Resistance of Streptococcus pneumoniae

We determined the nucleotide sequence between 1,903 and 3,097 bp of pbp1a, which encodes the transpeptidase domain of PBP 1A, from clinical isolates of penicillin-resistant Streptococcus pneumoniae (PRSP) serotypes 19 (n = 8), 6 (n = 9), 23 (n = 6), and 14 (n = 2) and two penicillin-susceptible S. p...

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Publicado en:Antimicrob Agents Chemother
Autores principales: Asahi, Yasuko, Ubukata, Kimiko
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 1998
Materias:
Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC105808/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9736547/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.42.9.2267
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