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Association of a Thr-371 Substitution in a Conserved Amino Acid Motif of Penicillin-Binding Protein 1A with Penicillin Resistance of Streptococcus pneumoniae

We determined the nucleotide sequence between 1,903 and 3,097 bp of pbp1a, which encodes the transpeptidase domain of PBP 1A, from clinical isolates of penicillin-resistant Streptococcus pneumoniae (PRSP) serotypes 19 (n = 8), 6 (n = 9), 23 (n = 6), and 14 (n = 2) and two penicillin-susceptible S. p...

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Pubblicato in:Antimicrob Agents Chemother
Autori principali: Asahi, Yasuko, Ubukata, Kimiko
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 1998
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC105808/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9736547/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.42.9.2267
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