Antimalarial Synergy of Cysteine and Aspartic Protease Inhibitors

It has been proposed that the Plasmodium falciparum cysteine protease falcipain and aspartic proteases plasmepsin I and plasmepsin II act cooperatively to hydrolyze hemoglobin as a source of amino acids for erythrocytic parasites. Inhibitors of each of these proteases have potent antimalarial effect...

Popoln opis

Bibliografske podrobnosti

izdano v:	Antimicrob Agents Chemother
Principais autores:	Semenov, Andrey, Olson, Jed E., Rosenthal, Philip J.
Format:	Artigo
Jezik:	Inglês
Izdano:	American Society for Microbiology (ASM) 1998
Teme:	Experimental Therapeutics
Online dostop:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC105801/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9736544/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.42.9.2254
Oznake:	Označite Brez oznak, prvi označite!