Bactericidal Activity of a Single-Dose Combination of Ofloxacin plus Minocycline, with or without Rifampin, against Mycobacterium leprae in Mice and in Lepromatous Patients

To develop a fully supervisable, monthly administered regimen for treatment of leprosy, the bactericidal effect of a single-dose combination of ofloxacin (OFLO) and minocycline (MINO), with or without rifampin (RMP), against Mycobacterium leprae was studied in the mouse footpad system and in previou...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Ji, Baohong, Sow, Samba, Perani, Evelyne, Lienhardt, Christian, Diderot, Vimala, Grosset, Jacques
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1998
Soggetti:	Experimental Therapeutics
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC105755/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9593137/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.42.5.1115
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