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Bactericidal Activity of a Single-Dose Combination of Ofloxacin plus Minocycline, with or without Rifampin, against Mycobacterium leprae in Mice and in Lepromatous Patients

To develop a fully supervisable, monthly administered regimen for treatment of leprosy, the bactericidal effect of a single-dose combination of ofloxacin (OFLO) and minocycline (MINO), with or without rifampin (RMP), against Mycobacterium leprae was studied in the mouse footpad system and in previou...

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Publicado en:Antimicrob Agents Chemother
Autores principales: Ji, Baohong, Sow, Samba, Perani, Evelyne, Lienhardt, Christian, Diderot, Vimala, Grosset, Jacques
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 1998
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC105755/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9593137/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.42.5.1115
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