Detection of Point Mutations in rpoB Gene of Rifampin-Resistant Rickettsia typhi

The rpoB gene of rifampin-resistant Rickettsia typhi (Rif mutant) and wild-type R. typhi were sequenced and compared. The Rif mutant rpoB had three nucleotide substitutions, which resulted in amino acid changes at residues 151, 201, and 271 and may be the basis for the rifampin resistance.

書誌詳細

出版年:	Antimicrob Agents Chemother
主要な著者:	Troyer, Jill Michelle, Radulovic, Suzana, Andersson, Siv G. E., Azad, Abdu F.
フォーマット:	Artigo
言語:	Inglês
出版事項:	American Society for Microbiology (ASM) 1998
主題:	Mechanisms of Resistance
オンライン･アクセス:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC105694/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9661032/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.42.7.1845
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