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Detection of Point Mutations in rpoB Gene of Rifampin-Resistant Rickettsia typhi

The rpoB gene of rifampin-resistant Rickettsia typhi (Rif mutant) and wild-type R. typhi were sequenced and compared. The Rif mutant rpoB had three nucleotide substitutions, which resulted in amino acid changes at residues 151, 201, and 271 and may be the basis for the rifampin resistance.

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Detalhes bibliográficos
Main Authors: Troyer, Jill Michelle, Radulovic, Suzana, Andersson, Siv G. E., Azad, Abdu F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC105694/
https://ncbi.nlm.nih.gov/pubmed/9661032
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