Chondrotoxicity and Toxicokinetics of Sparfloxacin in Juvenile Rats

Sparfloxacin is a fluoroquinolone with improved antibacterial activity against gram-positive pathogens. Like other quinolones, use of this drug is contraindicated in children and adolescents because of its potential chondrotoxicity in juveniles. We performed histological and immunohistochemical stud...

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Publié dans:	Antimicrob Agents Chemother
Auteurs principaux:	Stahlmann, Ralf, Zippel, Uta, Förster, Christian, Schwabe, Rudolf, Shakibaei, Mehdi, Merker, Hans-Joachim, Borner, Klaus
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Microbiology (ASM) 1998
Sujets:	Pharmacology
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC105624/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9624496/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.42.6.1470
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