Changes in MIC Alter Responses of Pseudomonas aeruginosa to Tobramycin Exposure

The pharmacokinetic parameters determining antibiotic efficacy are peak concentrations (C(max)), minimum (trough) concentrations (C(min)), and area under the concentration-time curve (AUC). There is general agreement about the importance of C(max) and AUC for aminoglycosides, but this is not so for...

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Detalles Bibliográficos

Publicado en:	Antimicrob Agents Chemother
Autores principales:	Ioannides-Demos, L. L., Liolios, L., Wood, P., Spicer, W. J., McLean, A. J.
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	American Society for Microbiology (ASM) 1998
Materias:	Pharmacology
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC105605/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9624477/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.42.6.1365
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