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Changes in MIC Alter Responses of Pseudomonas aeruginosa to Tobramycin Exposure

The pharmacokinetic parameters determining antibiotic efficacy are peak concentrations (C(max)), minimum (trough) concentrations (C(min)), and area under the concentration-time curve (AUC). There is general agreement about the importance of C(max) and AUC for aminoglycosides, but this is not so for...

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Bibliografiska uppgifter
Huvudupphovsmän: Ioannides-Demos, L. L., Liolios, L., Wood, P., Spicer, W. J., McLean, A. J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 1998
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC105605/
https://ncbi.nlm.nih.gov/pubmed/9624477
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