Alginate Lyase Promotes Diffusion of Aminoglycosides through the Extracellular Polysaccharide of Mucoid Pseudomonas aeruginosa

We demonstrated that a 2% suspension of Pseudomonas aeruginosa alginate completely blocked the diffusion of gentamicin and tobramycin, but not that of carbenicillin, illustrating how alginate production can help protect P. aeruginosa growing within alginate microcolonies in patients with cystic fibr...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Hatch, Richard A., Schiller, Neal L.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1998
Soggetti:	Susceptibility
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC105585/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9559826/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.42.4.974
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