Human Cytomegalovirus Mutant with Sequence-Dependent Resistance to the Phosphorothioate Oligonucleotide Fomivirsen (ISIS 2922)

A human cytomegalovirus mutant that was isolated for resistance (10-fold) to the antisense oligonucleotide fomivirsen (ISIS 2922) exhibited cross-resistance to a modified derivative of fomivirsen with an identical base sequence but little or no resistance to an oligonucleotide with an unrelated sequ...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Mulamba, Gilbert B., Hu, André, Azad, Raana F., Anderson, Kevin P., Coen, Donald M.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1998
Assuntos:	Antiviral Agents
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC105584/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9559825/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.42.4.971
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