Cyclosporin Analogs Inhibit In Vitro Growth of Cryptosporidium parvum

Cyclosporine and nonimmunosuppressive cyclosporin (CS) analogs were demonstrated to be potent inhibitors of the growth of the intracellular parasite Cryptosporidium parvum in short-term (48-h) in vitro cultures. Fifty-percent inhibitory concentrations (IC(50)s) were 0.4 μM for SDZ 033-243, 1.0 μM fo...

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Détails bibliographiques
Auteurs principaux: Perkins, Margaret E., Wu, Teresa W., Le Blancq, Sylvie M.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 1998
Sujets:
Susceptibility
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC105553/
https://ncbi.nlm.nih.gov/pubmed/9559794
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