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Cyclosporin Analogs Inhibit In Vitro Growth of Cryptosporidium parvum

Cyclosporine and nonimmunosuppressive cyclosporin (CS) analogs were demonstrated to be potent inhibitors of the growth of the intracellular parasite Cryptosporidium parvum in short-term (48-h) in vitro cultures. Fifty-percent inhibitory concentrations (IC(50)s) were 0.4 μM for SDZ 033-243, 1.0 μM fo...

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Udgivet i:Antimicrob Agents Chemother
Principais autores: Perkins, Margaret E., Wu, Teresa W., Le Blancq, Sylvie M.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1998
Fag:
Susceptibility
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC105553/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9559794/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.42.4.843
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