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Generation and Characterization of a Mutant of Influenza A Virus Selected with the Neuraminidase Inhibitor BCX-140

Influenza neuraminidase (NA) plays an important role in viral replication, and characterization of viruses resistant to NA inhibitors will help elucidate the role of active-site residues. This information will assist in designing better inhibitors targeted to essential active-site residues that cann...

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Main Authors: Bantia, Shanta, Ghate, Anita A., Ananth, Sandya L., Babu, Y. Sudhakar, Air, Gillian M., Walsh, Gerald M.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 1998
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC105545/
https://ncbi.nlm.nih.gov/pubmed/9559786
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