In Vitro and In Vivo Antifungal Activity of Amphotericin B Lipid Complex: Are Phospholipases Important?

Amphotericin B lipid complex for injection (ABLC) is a suspension of amphotericin B complexed with the lipids l-α-dimyristoylphosphatidylcholine (DMPC) and l-α-dimyristoylphosphatidylglycerol. ABLC is less toxic than amphotericin B deoxycholate (AmB-d), while it maintains the antifungal activity of...

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Bibliographic Details
Main Authors: Swenson, Christine E., Perkins, Walter R., Roberts, Patricia, Ahmad, Imran, Stevens, Rachel, Stevens, David A., Janoff, Andrew S.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 1998
Subjects:
Mechanisms of Resistance
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC105539/
https://ncbi.nlm.nih.gov/pubmed/9559780
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