Role of ABC Transporters in Aureobasidin A Resistance
Aureobasidin A (AbA) has strong antifungal effects arising from an unusual mechanism. We show that AbA interacts with ATP-binding cassette (ABC) transporters in yeast and mammalian cells. We isolated a gene of Saccharomyces cerevisiae that conferred resistance to AbA when the gene was present in mul...
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| Publicado no: | Antimicrob Agents Chemother |
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| Principais autores: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology (ASM)
1998
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC105537/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9559778/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.42.4.755 |
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