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Role of ABC Transporters in Aureobasidin A Resistance

Aureobasidin A (AbA) has strong antifungal effects arising from an unusual mechanism. We show that AbA interacts with ATP-binding cassette (ABC) transporters in yeast and mammalian cells. We isolated a gene of Saccharomyces cerevisiae that conferred resistance to AbA when the gene was present in mul...

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Dettagli Bibliografici
Pubblicato in:Antimicrob Agents Chemother
Autori principali: Ogawa, Atsuko, Hashida-Okado, Takashi, Endo, Masahiro, Yoshioka, Hirofumi, Tsuruo, Takashi, Takesako, Kazutoh, Kato, Ikunoshin
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 1998
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC105537/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9559778/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.42.4.755
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