Use of Pharmacodynamic Parameters To Predict Efficacy of Combination Therapy by Using Fractional Inhibitory Concentration Kinetics

Combination therapy with antimicrobial agents can be used against bacteria that have reduced susceptibilities to single agents. We studied various tobramycin and ceftazidime dosing regimens against four resistant Pseudomonas aeruginosa strains in an in vitro pharmacokinetic model to determine the us...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	den Hollander, Jan G., Mouton, Johan W., Verbrugh, Henri A.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1998
Assuntos:	Pharmacology
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC105535/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9559776/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.42.4.744
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