KY-62, a Polyene Analog of Amphotericin B, for Treatment of Murine Candidiasis

KY-62 is a water-soluble analog of amphotericin B. In vitro testing of five clinical isolates of Candida albicans showed KY-62 to have potency similar to that of amphotericin B. KY-62 was administered to mice infected intravenously with C. albicans. In vivo, KY-62 was effective in immunocompetent mi...

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Hlavní autoři: Graybill, John R., Najvar, Laura K., Fothergill, Annette, Hardin, Thomas, Rinaldi, Michael, Lambros, Chris, Regen, Steven L.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 1998
Témata:
Experimental Therapeutics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC105470/
https://ncbi.nlm.nih.gov/pubmed/9449275
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