KY-62, a Polyene Analog of Amphotericin B, for Treatment of Murine Candidiasis

KY-62 is a water-soluble analog of amphotericin B. In vitro testing of five clinical isolates of Candida albicans showed KY-62 to have potency similar to that of amphotericin B. KY-62 was administered to mice infected intravenously with C. albicans. In vivo, KY-62 was effective in immunocompetent mi...

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Podrobná bibliografie

Vydáno v:	Antimicrob Agents Chemother
Hlavní autoři:	Graybill, John R., Najvar, Laura K., Fothergill, Annette, Hardin, Thomas, Rinaldi, Michael, Lambros, Chris, Regen, Steven L.
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology (ASM) 1998
Témata:	Experimental Therapeutics
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC105470/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9449275/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.42.1.147
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