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Critical Importance of In Vivo Amoxicillin and Cefotaxime Concentrations for Synergy in Treatment of Experimental Enterococcus faecalis Endocarditis

The synergy between amoxicillin and cefotaxime against two strains of Enterococcus faecalis (JH2-2 and 6370) in vitro and in rabbit endocarditis was investigated. In vitro synergy was obtained only when amoxicillin concentrations were below the MBC and when cefotaxime concentrations were above 1 μg/...

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Bibliographische Detailangaben
Hauptverfasser: Join-Lambert, Olivier, Mainardi, Jean-Luc, Cuvelier, Catherine, Dautrey, Sophie, Farinotti, Robert, Fantin, Bruno, Carbon, Claude
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 1998
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC105439/
https://ncbi.nlm.nih.gov/pubmed/9527811
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