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Critical Importance of In Vivo Amoxicillin and Cefotaxime Concentrations for Synergy in Treatment of Experimental Enterococcus faecalis Endocarditis

The synergy between amoxicillin and cefotaxime against two strains of Enterococcus faecalis (JH2-2 and 6370) in vitro and in rabbit endocarditis was investigated. In vitro synergy was obtained only when amoxicillin concentrations were below the MBC and when cefotaxime concentrations were above 1 μg/...

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Detalhes bibliográficos
Main Authors: Join-Lambert, Olivier, Mainardi, Jean-Luc, Cuvelier, Catherine, Dautrey, Sophie, Farinotti, Robert, Fantin, Bruno, Carbon, Claude
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC105439/
https://ncbi.nlm.nih.gov/pubmed/9527811
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