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Toward transcriptional therapies for the failing heart: chemical screens to modulate genes
In response to acute and chronic stresses, the heart frequently undergoes a remodeling process that is accompanied by myocyte hypertrophy, impaired contractility, and pump failure, often culminating in sudden death. The existence of redundant signaling pathways that trigger heart failure poses chall...
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| 主要な著者: | , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Clinical Investigation
2005
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1052006/ https://ncbi.nlm.nih.gov/pubmed/15765135 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200524144 |
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