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The 12 base pair duplication/insertion alteration could be a regulatory mutation.

A wide array of mutations now numbering more than 200 have been identified in the BRCA1 gene, one of the two breast cancer susceptibility genes identified so far. In addition, there have been several variants described but it is not known if they really represent functionally significant mutations o...

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Detalhes bibliográficos
Main Authors: Robledo, M, Osorio, A, Sentís, C, Albertos, J, Estevez, L, Benítez, J
Formato: Artigo
Idioma:Inglês
Publicado em: 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1051003/
https://ncbi.nlm.nih.gov/pubmed/9222971
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