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Germline HNPCC gene variants have little influence on the risk for sporadic colorectal cancer.

Hereditary non-polyposis colorectal cancer (HNPCC) is a syndrome of inherited bowel and other cancers that has been said to account for up to 15% of all colorectal carcinomas (CRCs). HNPCC can now be diagnosed at the molecular level by detecting germline mutations in genes involved in mismatch repai...

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Detalhes bibliográficos
Main Authors: Tomlinson, I P, Beck, N E, Homfray, T, Harocopos, C J, Bodmer, W F
Formato: Artigo
Idioma:Inglês
Publicado em: 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1050845/
https://ncbi.nlm.nih.gov/pubmed/9032648
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