Interleukin-18 Protects Mice against Acute Herpes Simplex Virus Type 1 Infection

We examined the effects of interleukin-18 (IL-18) in a mouse model of acute intraperitoneal infection with herpes simplex virus type 1 (HSV-1). Four days of treatment with IL-18 (from 2 days before infection to 1 day after infection) improved the survival rate of BALB/c, BALB/c nude, and BALB/c SCID...

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Main Authors: Fujioka, Noboru, Akazawa, Rieko, Ohashi, Kunihiro, Fujii, Mitsukiyo, Ikeda, Masao, Kurimoto, Masashi
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 1999
Assuntos:
Pathogenesis and Immunity
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC104486/
https://ncbi.nlm.nih.gov/pubmed/9971824
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