Interleukin-18 Protects Mice against Acute Herpes Simplex Virus Type 1 Infection

We examined the effects of interleukin-18 (IL-18) in a mouse model of acute intraperitoneal infection with herpes simplex virus type 1 (HSV-1). Four days of treatment with IL-18 (from 2 days before infection to 1 day after infection) improved the survival rate of BALB/c, BALB/c nude, and BALB/c SCID...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Fujioka, Noboru, Akazawa, Rieko, Ohashi, Kunihiro, Fujii, Mitsukiyo, Ikeda, Masao, Kurimoto, Masashi
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1999
Assuntos:	Pathogenesis and Immunity
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC104486/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9971824/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.3.2401-2409.1999
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