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V3 Recombinants Indicate a Central Role for CCR5 as a Coreceptor in Tissue Infection by Human Immunodeficiency Virus Type 1

Binding of the human immunodeficiency virus type 1 (HIV-1) envelope glycoprotein gp120 to both CD4 and one of several chemokine receptors (coreceptors) permits entry of virus into target cells. Infection of tissues may establish latent viral reservoirs as well as cause direct pathologic effects that...

詳細記述

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書誌詳細
主要な著者: Chan, Stephen Y., Speck, Roberto F., Power, Christopher, Gaffen, Sarah L., Chesebro, Bruce, Goldsmith, Mark A.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 1999
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC104480/
https://ncbi.nlm.nih.gov/pubmed/9971818
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