Hypoxia Blocks In Vivo Initiation of Simian Virus 40 Replication at a Stage Preceding Origin Unwinding

Simian virus 40 (SV40)-infected CV1 cells transiently exposed to hypoxia show a burst of viral replication immediately after reoxygenation. DNA precursor incorporation and analysis of growing daughter strands by alkaline sedimentation demonstrated that SV40 DNA synthesis began with a lag of about 3...

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Main Authors: Riedinger, Hans-Jörg, van Betteraey, Maria, Probst, Hans
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 1999
Teme:
Replication
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC104469/
https://ncbi.nlm.nih.gov/pubmed/9971807
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