Extensive Mutagenesis of the Hepatitis B Virus Core Gene and Mapping of Mutations That Allow Capsid Formation

We generated a large number of mutations in the hepatitis B virus (HBV) core gene inserted into a bacterial expression vector. The new mutagenesis procedure generated deletions and insertions (as sequence repeats) of various lengths at random positions between M1 and E145 but not substitutions. The...

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Vydáno v:	J Virol
Hlavní autoři:	Koschel, Matthias, Thomssen, Reiner, Bruss, Volker
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology (ASM) 1999
Témata:	Structure and Assembly
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC104460/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9971798/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.3.2153-2160.1999
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