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Human Immunodeficiency Virus Type 1 Tat Induces Apoptosis and Increases Sensitivity to Apoptotic Signals by Up-Regulating FLICE/Caspase-8

Apoptosis contributes to the loss of CD4 cells during human immunodeficiency virus type 1 (HIV-1) infection. Although the product of the env gene, gp160/gp120, is known to play a role in cell death mediated by HIV-1, the role of other HIV-1 genes in the process is unclear. We found that HIV-1 lackin...

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Pubblicato in:J Virol
Autori principali: Bartz, Steven R., Emerman, Michael
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 1999
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC104437/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9971775/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.3.1956-1963.1999
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