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Functional Interactions of the HHCC Domain of Moloney Murine Leukemia Virus Integrase Revealed by Nonoverlapping Complementation and Zinc-Dependent Dimerization

The retroviral integrase (IN) is required for the integration of viral DNA into the host genome. The N terminus of IN contains an HHCC zinc finger-like motif, which is conserved among all retroviruses. To study the function of the HHCC domain of Moloney murine leukemia virus IN, the first N-terminal...

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Bibliografiske detaljer
Udgivet i:J Virol
Principais autores: Yang, Fan, Leon, Oscar, Greenfield, Norma J., Roth, Monica J.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1999
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC104420/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9971758/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.3.1809-1817.1999
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