pH-Dependent Changes in Photoaffinity Labeling Patterns of the H1 Influenza Virus Hemagglutinin by Using an Inhibitor of Viral Fusion

The hemagglutinin (HA) protein undergoes a low-pH-induced conformational change in the acidic milieu of the endosome, resulting in fusion of viral and cellular membranes. A class of compounds that specifically interact with the HA protein of H1 and H2 subtype viruses and inhibit this conformational...

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Hlavní autoři: Cianci, Christopher, Yu, Kuo-Long, Dischino, Douglas D., Harte, William, Deshpande, Milind, Luo, Guangxiang, Colonno, Richard J., Meanwell, Nicholas A., Krystal, Mark
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 1999
Témata:
Vaccines and Antiviral Agents
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC104417/
https://ncbi.nlm.nih.gov/pubmed/9971755
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