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pH-Dependent Changes in Photoaffinity Labeling Patterns of the H1 Influenza Virus Hemagglutinin by Using an Inhibitor of Viral Fusion

The hemagglutinin (HA) protein undergoes a low-pH-induced conformational change in the acidic milieu of the endosome, resulting in fusion of viral and cellular membranes. A class of compounds that specifically interact with the HA protein of H1 and H2 subtype viruses and inhibit this conformational...

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Detalhes bibliográficos
Publicado no:J Virol
Principais autores: Cianci, Christopher, Yu, Kuo-Long, Dischino, Douglas D., Harte, William, Deshpande, Milind, Luo, Guangxiang, Colonno, Richard J., Meanwell, Nicholas A., Krystal, Mark
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC104417/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9971755/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.3.1785-1794.1999
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