Protein Kinase B Localization and Activation Differentially Affect S6 Kinase 1 Activity and Eukaryotic Translation Initiation Factor 4E-Binding Protein 1 Phosphorylation

Recent studies indicate that phosphatidylinositide-3OH kinase (PI3K)-induced S6 kinase (S6K1) activation is mediated by protein kinase B (PKB). Support for this hypothesis has largely relied on results obtained with highly active, constitutively membrane-localized alleles of wild-type PKB, whose act...

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Pubblicato in:	Mol Cell Biol
Autori principali:	Dufner, Almut, Andjelkovic, Mirjana, Burgering, Boudewijn M. T., Hemmings, Brian A., Thomas, George
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Taylor & Francis 1999
Soggetti:	Cell Growth and Development
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC104410/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10330191/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.19.6.4525
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