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Basis for the Checkpoint Signal Specificity That Regulates Chk1 and Cds1 Protein Kinases

Six checkpoint Rad proteins (Rad1, Rad3, Rad9, Rad17, Rad26, and Hus1) are needed to regulate checkpoint protein kinases Chk1 and Cds1 in fission yeast. Chk1 is required to prevent mitosis when DNA is damaged by ionizing radiation (IR), whereas either kinase is sufficient to prevent mitosis when DNA...

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Udgivet i:Mol Cell Biol
Principais autores: Brondello, Jean-Marc, Boddy, Michael N., Furnari, Beth, Russell, Paul
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 1999
Fag:
Cell Growth and Development
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC104386/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10330167/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.19.6.4262
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