Ku Antigen-DNA Conformation Determines the Activation of DNA-Dependent Protein Kinase and DNA Sequence-Directed Repression of Mouse Mammary Tumor Virus Transcription

Mouse mammary tumor virus (MMTV) transcription is repressed by DNA-dependent protein kinase (DNA-PK) through a DNA sequence element, NRE1, in the viral long terminal repeat that is a sequence-specific DNA binding site for the Ku antigen subunit of the kinase. While Ku is an essential component of th...

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Hlavní autoři: Giffin, Ward, Gong, Wenrong, Schild-Poulter, Caroline, Haché, Robert J. G.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 1999
Témata:
Transcriptional Regulation
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC104366/
https://ncbi.nlm.nih.gov/pubmed/10330147
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