R5 Strains of Human Immunodeficiency Virus Type 1 from Rapid Progressors Lacking X4 Strains Do Not Possess X4-Type Pathogenicity in Human Thymus

Some individuals infected with only R5 strains of human immunodeficiency virus type 1 progress to AIDS as quickly as individuals harboring X4 strains. We determined that three R5 viruses were much less pathogenic than an X4 virus in SCID-hu Thy/Liv mice, suggesting that R5 virus-mediated rapid disea...

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Hlavní autoři: Berkowitz, Robert D., van ’t Wout, Angélique B., Kootstra, Neeltje A., Moreno, Mary E., Linquist-Stepps, Valerie D., Bare, Christopher, Stoddart, Cheryl A., Schuitemaker, Hanneke, McCune, Joseph M.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 1999
Témata:
Pathogenesis and Immunity
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC104310/
https://ncbi.nlm.nih.gov/pubmed/10438873
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