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Pathogenesis of Chimeric MHV4/MHV-A59 Recombinant Viruses: the Murine Coronavirus Spike Protein Is a Major Determinant of Neurovirulence

The mouse hepatitis virus (MHV) spike glycoprotein, S, has been implicated as a major determinant of viral pathogenesis. In the absence of a full-length molecular clone, however, it has been difficult to address the role of individual viral genes in pathogenesis. By using targeted RNA recombination...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Phillips, Joanna J., Chua, Ming Ming, Lavi, Ehud, Weiss, Susan R.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society for Microbiology 1999
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC104302/
https://ncbi.nlm.nih.gov/pubmed/10438865
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