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Antibody-Independent Protection against Rotavirus Infection of Mice Stimulated by Intranasal Immunization with Chimeric VP4 or VP6 Protein

This study was to determine whether individual rotavirus capsid proteins could stimulate protection against rotavirus shedding in an adult mouse model. BALB/c mice were intranasally or intramuscularly administered purified Escherichia coli-expressed murine rotavirus strain EDIM VP4, VP6, or truncate...

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Bibliographic Details
Main Authors: Choi, Anthony H.-C., Basu, Mitali, McNeal, Monica M., Clements, John D., Ward, Richard L.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 1999
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC104284/
https://ncbi.nlm.nih.gov/pubmed/10438847
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