Inhibitory Activity of Constitutive Nitric Oxide on the Expression of Alpha/Beta Interferon Genes in Murine Peritoneal Macrophages

We investigated the role of the constitutive nitric oxide (NO) in the expression of interferon (IFN) genes in mouse peritoneal macrophages (PM). The treatment of PM with l-arginine-N(G)-amine (AA), a potent inhibitor of NO-producing enzymes, resulted in a marked accumulation of IFN-α4 mRNA and, to a...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Guillemard, Eric, Varano, Barbara, Belardelli, Filippo, Quero, A. M., Gessani, Sandra
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1999
Assuntos:	Pathogenesis and Immunity
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC104258/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10438821/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.9.7328-7333.1999
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