Inhibitory Activity of Constitutive Nitric Oxide on the Expression of Alpha/Beta Interferon Genes in Murine Peritoneal Macrophages

We investigated the role of the constitutive nitric oxide (NO) in the expression of interferon (IFN) genes in mouse peritoneal macrophages (PM). The treatment of PM with l-arginine-N(G)-amine (AA), a potent inhibitor of NO-producing enzymes, resulted in a marked accumulation of IFN-α4 mRNA and, to a...

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Bibliografske podrobnosti

izdano v:	J Virol
Principais autores:	Guillemard, Eric, Varano, Barbara, Belardelli, Filippo, Quero, A. M., Gessani, Sandra
Format:	Artigo
Jezik:	Inglês
Izdano:	American Society for Microbiology (ASM) 1999
Teme:	Pathogenesis and Immunity
Online dostop:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC104258/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10438821/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.9.7328-7333.1999
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