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Deletion of the R78 G Protein-Coupled Receptor Gene from Rat Cytomegalovirus Results in an Attenuated, Syncytium-Inducing Mutant Strain

The rat cytomegalovirus (RCMV) R78 gene belongs to an uncharacterized class of viral G protein-coupled receptor (GCR) genes. The predicted amino acid sequence of the R78 open reading frame (ORF) shows 25 and 20% similarity with the gene products of murine cytomegalovirus M78 and human cytomegaloviru...

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Pubblicato in:J Virol
Autori principali: Beisser, Patrick S., Grauls, Gert, Bruggeman, Cathrien A., Vink, Cornelis
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 1999
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC104246/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10438809/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.9.7218-7230.1999
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