The r144 Major Histocompatibility Complex Class I-Like Gene of Rat Cytomegalovirus Is Dispensable for both Acute and Long-Term Infection in the Immunocompromised Host

The rat cytomegalovirus (RCMV) r144 gene encodes a polypeptide homologous to major histocompatibility complex class I heavy chains. To study the role of r144 in virus replication, an RCMV r144 null mutant strain (RCMVΔr144) was generated. This strain replicated with efficiency similar to that of wil...

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Pubblicato in:	J Virol
Autori principali:	Beisser, Patrick S., Kloover, Jeroen S., Grauls, Gert E. L. M., Blok, Marinus J., Bruggeman, Cathrien A., Vink, Cornelis
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 2000
Soggetti:	Pathogenesis and Immunity
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC111630/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10623772/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.74.2.1045-1050.2000
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