The r144 Major Histocompatibility Complex Class I-Like Gene of Rat Cytomegalovirus Is Dispensable for both Acute and Long-Term Infection in the Immunocompromised Host

The rat cytomegalovirus (RCMV) r144 gene encodes a polypeptide homologous to major histocompatibility complex class I heavy chains. To study the role of r144 in virus replication, an RCMV r144 null mutant strain (RCMVΔr144) was generated. This strain replicated with efficiency similar to that of wil...

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Bibliographic Details
Main Authors: Beisser, Patrick S., Kloover, Jeroen S., Grauls, Gert E. L. M., Blok, Marinus J., Bruggeman, Cathrien A., Vink, Cornelis
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2000
Subjects:
Pathogenesis and Immunity
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC111630/
https://ncbi.nlm.nih.gov/pubmed/10623772
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