Immunization with a Live, Attenuated Simian Immunodeficiency Virus Vaccine Leads to Restriction of Viral Diversity in Rhesus Macaques Not Protected from Pathogenic Challenge

Rhesus macaques immunized with simian immunodeficiency virus SIVmac239Δnef but not protected from SIVmac251 challenge were studied to determine the genetic and biological characteristics of the breakthrough viruses. Assessment of SIV genetic diversity (env V1-V2) revealed a reduction in the number o...

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Veröffentlicht in:	J Virol
Hauptverfasser:	Sodora, Donald L., Sheridan, Kristine E., Marx, Preston A., Connor, Ruth I.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1999
Schlagworte:	Vaccines and Antiviral Agents
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC104226/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10196343/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.5.4443-4446.1999
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