Immunization with a Live, Attenuated Simian Immunodeficiency Virus Vaccine Leads to Restriction of Viral Diversity in Rhesus Macaques Not Protected from Pathogenic Challenge

Rhesus macaques immunized with simian immunodeficiency virus SIVmac239Δnef but not protected from SIVmac251 challenge were studied to determine the genetic and biological characteristics of the breakthrough viruses. Assessment of SIV genetic diversity (env V1-V2) revealed a reduction in the number o...

詳細記述

書誌詳細

出版年:	J Virol
主要な著者:	Sodora, Donald L., Sheridan, Kristine E., Marx, Preston A., Connor, Ruth I.
フォーマット:	Artigo
言語:	Inglês
出版事項:	American Society for Microbiology (ASM) 1999
主題:	Vaccines and Antiviral Agents
オンライン･アクセス:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC104226/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10196343/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.5.4443-4446.1999
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