The Amino-Terminal Region of Vpr from Human Immunodeficiency Virus Type 1 Forms Ion Channels and Kills Neurons

We have previously reported that the accessory protein Vpr from human immunodeficiency virus type 1 forms cation-selective ion channels in planar lipid bilayers and is able to depolarize intact cultured neurons by causing an inward sodium current, resulting in cell death. In this study, we used site...

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Main Authors: Piller, S. C., Ewart, G. D., Jans, D. A., Gage, P. W., Cox, G. B.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 1999
Teme:
Virus-Cell Interactions
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC104202/
https://ncbi.nlm.nih.gov/pubmed/10196319
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